Cadherin-16 anticorps
Aperçu rapide pour Cadherin-16 anticorps (ABIN6297278)
Antigène
Voir toutes Cadherin-16 (CDH16) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- Mouse anti-Human/Mouse/Rat/Rabbit/Dog Cadherin 16 Antibody [Sodium Azide Free]
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Specificité
- Cell surface with some cytoplasmic
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Purification
- Recombinant human protein was used as the immunogen for the anti-Cadherin 16 antibody.
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Immunogène
- Recombinant human protein was used as the immunogen for the anti-Cadherin 16 antibody.
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Indications d'application
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Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 1-2 μg/mL
Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 min at RT (1)
Prediluted format: incubate for 30 min at RT (2) -
Restrictions
- For Research Use only
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Buffer
- In 1X PBS, BSA free, sodium azide free
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Agent conservateur
- Azide free
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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- Cadherin-16 (CDH16)
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Autre désignation
- Cadherin-16
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Sujet
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Target Description: This mAb recognizes a protein of 130 kDa, identified as Ksp-cadherin. Cadherins form a superfamily of related glycoproteins that mediate calcium-dependent cell adhesion and transmit signals from the extracellular matrix to the cytoplasm. Cadherins have been implicated in embryogenesis, tissue morphogenesis, tissue structure maintenance, cell polarization, neoplastic invasiveness and metastasis, and membrane transport. It is suggested that Ksp-cadherin is a marker for terminal differentiation of the basolateral membranes of renal tubular epithelial cells. Within the kidney, Ksp-Cadherin is found exclusively in the basolateral membrane of renal tubular epithelial cells and collecting duct cells, and not in glomeruli, renal interstitial cells, or blood vessels. Ksp-Cadherin has been suggested to distinguish Chromophobe Renal-Cell Carcinoma from Oncocytoma.
Gene Symbol: CDH16///UNQ695///PRO1340
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ID gène
- 1014
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UniProt
- O75309
Antigène
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